There are certainly wolves worth playing, like Cemetery Prowler for a nice combination of ramp and graveyard hate, and Anara, Wolvid Familiar for protection
Many cards that hate on nonbasic lands are good sideboard pieces, but some of them can be played in the main deck depending on the metagame or how well you can break parity on their effects
It adds an extra layer of security and peace of mind, knowing that your collection is safe and well-contained
That means that theres a decent chance at least one player in a game of Commander wont be able to block the creature this is attached to, giving you an easy route to untap your lands
Creatures like Venser, Shaper Savant, and Hullbreaker Horror can easily serve as removal, all while providing a combat-ready body