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CAS Number: 121058-88-6
InChiKey: IUWKNLFTJBHTSD-QXUNDURPSA-N
Smiles: OC[C@H]1O[C@H](OP(O)(O)=O)[C@H](O)[C@@H](O)[C@H]1O
50:190-200
Chemical Name: 2-[(3S)-1-[5-(cyclohexylcarbamoyl)-6-propylsulfanylpyridin-2-yl]-3-piperidyl]acetic acid
PF-5006739 Size:Contact [email protected] for quotation CAS Number: 121058-88-6PF 5006739 is a potent and selective inhibitor of CK1 with IC50s of 3. 9 nM and 17. 0 nM, respectively. PF 5006739 is a potential therapeutic agent for a range of psychiatric disorders with low nanomolar in vitro potency for CK1 and high kinome selectivity. PF 5006739 attenuats opioid drug seeking behavior in a rodent operant reinstatement model in animals in a dose dependent manner. PF 5006739 improves glucose tolerance in both diet induced obesity
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