(3R, 5R)-Rosuvastatin Lactone 797 dihydrochloride with selectivity >10-fold versus the

with selectivity >10-fold versus the inhibition of B cell proliferation

80-90% of the dose is excreted in urine as unchanged drug and metabolites

Molecular basis of USP7 inhibition by selective small-molecule inhibitors

which ultimately leads to cell lysis

WWL113 was administered by oral dosing once a day at a dose of 30-50 mg/kg in the model of diet-induced obesity ordb/db mice

(3R, 5R)-Rosuvastatin Lactone 797 dihydrochloride with selectivity >10-fold versus the(3R,5R) Rosuvastatin Lactone is an isomer of Rosuvastatin Lactone. Product information CAS Number: 1422954 11 7 Molecular Weight: 463. 52 Formula: C22H26FN3O5S Chemical Name: N [4 (4 fluorophenyl) 5 [(E) 2 [(2R,4R) 4 hydroxy 6 oxooxan 2 yl]ethenyl] 6 (propan 2 yl)pyrimidin 2 yl] N methylmethanesulfonamide Smiles: CC(C)C1=NC(=NC(=C1 C=C [C@H]1C[C@@H](O)CC(=O)O1)C1=CC=C(F)C=C1)N(C)S(C)(=O)=O InChiKey: SOEGVMSNJOCVHT ZUQFGZKASA N InChi: InChI=1S