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RG13022 suppresses tumor growth in nude mice
25)/t10-/m0/s1
IC50 value: Target: cathepsin K The cathepsin K inhibitor AAE-581 (balicatib) as the most advanced of them passed Phase II clinical trials in 2005
16% in PANC-1 cells
Cereblon ligand 3
Mavacamten ative RG13022 suppresses tumor growth inMavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively. Product information CAS Number: 1642288 47 8 Molecular Weight: 273. 33 Formula: C15H19N3O2 Chemical Name: 6 {[(1S) 1 phenylethyl]amino} 3 (propan 2 yl) 1,2,3,4 tetrahydropyrimidine 2,4 dione Smiles: CC(C)N1C(=O)NC(=CC1=O)N[C@@H](C)C1C=CC=CC=1 InChiKey: RLCLASQCAPXVLM NSHDSACASA N InChi: InChI=1S C15H19N3O2
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