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PF-00562271 EG5-Tos (2013) Cell Stem Cell

SKU: 54937414397

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Description

(2013) Cell Stem Cell

IWR-1 exerts its effect via interaction with Axin

decreased cell proliferation

ML-329 shows specific activity against the MITF-dependent cells

IOX1 inhibits JMJD2A-mediated H3K9me3 demethylation in HeLa cells

PF-00562271 EG5-Tos (2013) Cell Stem CellPF 562271, also known as PF 562, 271 and PF 271, is an orally bioavailable small molecule and ATP competitive focal adhesion kinase (FAK) inhibitor with potential antineoplastic and antiangiogenic activities. PF 562271 inhibits the tyrosine kinase FAK, and to a lesser extent, proline rich tyrosine kinase (PYK2), which may inhibit tumor cell migration, proliferation, and survival. Product information CAS Number: 717907 75 0 Molecular Weight: 507. 49

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