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with TGI of 88% and 97%
These results indicate CI-1040 exerts its effects on cells by suppressing the activation of MKK1
3-dimethyl-1-oxobutan-2-yl)amino)-7-oxoheptyl)amino)-2-oxoethoxy)phenyl)propyl (S)-1-((S)-2-(3
as well as the endoplasmic reticulum stress response
72C:243-253
Obatoclax (GX15-070) Size:2mg solid with TGI of 88% andObatoclax, also known as GX 015 070, a synthetic small molecule inhibitor of the bcl 2 family of proteins with potential pro apoptotic and antineoplastic activities. Obatoclax binds to members of the Bcl 2 protein family, preventing the binding of these anti apoptotic proteins to the pro apoptotic proteins Bax and Bak and so promoting the activation of the apoptotic pathway in Bcl 2 overexpressing cells. The Bcl 2 family of proteins (bcl 2, bcl xl,
US$ 224.50
US$ 362.00
US$ 162.00