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Canagliflozin inhibits Na+-dependent 14C-AMG uptake in CHO-hSGLT2 cells
diminishes glutamate and α-KG levels
Protein co-crystal structures demonstrate that TH588 binds in the active site of MTH1
promotes G0-G1 cell-cycle arrest
UCB9608 is a potent immunosuppressive agent that improves metabolic stability and exhibits excellent pharmacokinetic profile
Semagacestat (LY450139) Size:2mg solid Canagliflozin inhibits Na+-dependent 14C-AMG uptakeSemagacestat, also known as LY450139 or LY4501; was a candidate drug for a causal therapy against Alzheimer's disease. Product information CAS Number: 425386 60 3 Molecular Weight: 361. 44 Formula: C19H27N3O4 Synonym: LY 4501 Chemical Name: (S) 2 hydroxy 3 methyl N ((S) 1 (((S) 3 methyl 2 oxo 2, 3, 4, 5 tetrahydro 1H benzo[d]azepin 1 yl)amino) 1 oxopropan 2 yl)butanamide Smiles: CC(C)[C@H](O)C(=O)N[C@@H](C)C(=O)N[C@H]1C2=CC=CC=C2CCN(C)C1=O InChiKey:
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