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Elubrixin tosylate in Dihydrochalcone PubMed Central PMCID: PMC3383737

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Description

PubMed Central PMCID: PMC3383737

SMER3 was used at 10-20 µM final concentration in various in vitro assays

Formula: C12H20O2

Rimiducid (AP1903

Formula: C15H21N3O3S

Elubrixin tosylate in Dihydrochalcone PubMed Central PMCID: PMC3383737Elubrixin tosylate (SB 656933 tosylate) is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL 8 receptor antagonist. Elubrixin tosylate inhibits neutrophil CD11b upregulation (IC50 of 260. 7 nM) and shape change (IC50 of 310. 5 nM). Elubrixin tosylate has the potential for inflammatory diseases research, such as inflammatory bowel disease and airway inflammation. Product information CAS Number: 960495 43 6

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