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PNU 37883 hydrochloride (PNU 37883A) is a selective vascular ATP-sensitive potassium (Kir6
Smiles: OC[C@@H]1O[C@@H](OC2C(=O)C3=C(C=C(O)C=C3O)OC=2C2C=CC(O)=CC=2)[C@H](O)[C@H]1O
5ClH/c26-22(27)18-1-3-19(4-2-18)23(35)31-9-11-32(12-10-31)24(36)20-13-17(14-21(15-20)34(37)38)16-30-5-7-33(8-6-30)25(28)29
antitumor activity was also observed in the human lung cancer model
In a separate experiment
Cytochalasin J Size:Contact [email protected] for quotation PNU 37883 hydrochloride (PNU 37883A)Cytochalasin J can alter mitotic spindle microtubule organization and kinetochore structure. The cytochalasins are cell permeable fungal metabolites inhibiting actin polymerization, which can alter diverse processes including cell movement, growth, phagocytosis, degranulation, and secretion. In vitro: Cytochalasin J was identified as a deacetylated analog of cytochalasin H that weakly inhibited actin assembly but significantly altered mitotic spindle
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