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PF-670462 2HCl - CAS# 950912-80-8 Catalog No.:M6553-10 GR148672X is a triacyglycerol hydrolase

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Description

GR148672X is a triacyglycerol hydrolase (TGH) inhibitor with an IC50 of 4 nM extracted from patent WO 2001016358 A2

CID-23631927

Leveridge M

YM-201636 at 160 nM inhibits PtdIns5P synthesis twice more effectively compared with PtdIns(3

U46619 and collagen

PF-670462 2HCl - CAS# 950912-80-8 Catalog No.:M6553-10 GR148672X is a triacyglycerol hydrolasePF 670462 2HCl, CAS No. 950912 80 8, is a potent inhibitor of the CK1 isoforms CK1 and CK1 (IC50 = 7. 7 and 14 nM, respectively). Inhibition of CKIepsilon yields a perturbation of oscillator function that forestalls light as a zeitgeber, and they demonstrate that pharmacological tools such as PF 670462 may yield valuable insight into clock function. Casein kinase Iepsilon (CKIepsilon) is an essential component of the biological clock, phosphorylating

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