Ralimetinib - CAS# 862505-00-8 S R S)-AHPC-PEG4-NH2 hydrochloride 39(2):543-9

39(2):543-9

84-tetracosazatricyclo[40

A (89)Zr-HDL PET tracer monitors response to a CSF1R inhibitor

Solubility: H2O : 125 mg/mL (180

Formula: C24H29F3N4O8S

Ralimetinib - CAS# 862505-00-8 S R S)-AHPC-PEG4-NH2 hydrochloride 39(2):543-9Ralimetinib (LY2228820) is a potent and selective, ATP competitive inhibitor of p38 MAPK , with IC50s of 5. 3 and 3. 2 nM, respectively. Ralimetinib (LY2228820) selectively inhibits phosphorylation of MK2 (Thr334), with no effect on phosphorylation of p38 MAPK, JNK, ERK1 2, c Jun, ATF2, or c Myc. Product information CAS Number: 862505 00 8 Molecular Weight: 420. 53 Formula: C24H29FN6 Chemical Name: 5 [2 tert butyl 4 (4 fluorophenyl) 1H imidazol 5 yl]