![ML218 hydrochloride Size:Contact sales@xcessbio.com for quotation 11]pentaoxa[2](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M19751_1635189689.gif?v=1635189690)
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11]pentaoxa[2
and insulin resistance in humans
H2O/c1-2-13-3-5-14(6-4-13)9-15-7-8-16-12-27-22(17(16)10-15)21(26)20(25)19(24)18(11-23)28-22
InChi: InChI=1S/C16H14FIN4O3/c17-13-7-10(18)1-4-14(13)20-15-12(16(24)21-25-6-5-23)3-2-11-8-19-9-22(11)15/h1-4
Gamache DA
ML218 hydrochloride Size:Contact [email protected] for quotation 11]pentaoxa[2ML218 hydrochloride is a potent, selective and orally active T type Ca2+ channels (Cav3. 1, Cav3. 2, Cav3. 3) inhibitor with IC50s of 310 nM and 270 nM for Cav3. 2 and Cav3. 3, respectively. ML218 hydrochloride inhibits the burst activity in subthalamic nucleus (STN) neurons. ML218 hydrochloride has no significant inhibition of L or N type calcium channels, KATP or hERG potassium channels. ML218 hydrochloride can penetrate the blood brain barrier.