CDK12-IN-3 13774 4-dihydroxyphenyl)ethylidene]-4-methylbenzohydrazide

4-dihydroxyphenyl)ethylidene]-4-methylbenzohydrazide

PAK3 and PAK4 respectively)

The reference for administration is 10 mg/kg

In cancer cells

and thus inhibits their biological function

CDK12-IN-3 13774 4-dihydroxyphenyl)ethylidene]-4-methylbenzohydrazideCDK12 IN 3 is a potent and selective CDK12 inhibitor with an IC50 of 491 nM in enzymatic assay. Product information CAS Number: 2220184 50 7 Molecular Weight: 470. 52 Formula: C23H28F2N8O Chemical Name: 2 [(2S) 1 (6 {[(6,7 difluoro 1H 1,3 benzodiazol 2 yl)methyl]amino} 9 (propan 2 yl) 9H purin 2 yl)piperidin 2 yl]ethan 1 ol Smiles: CC(C)N1C=NC2C1=NC(=NC=2NCC1NC2=C(C=CC(F)=C2F)N=1)N1CCCC[C@H]1CCO InChiKey: KULPPFCRBINTBS AWEZNQCLSA N InChi: InChI=1S