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Abstract #250
InChiKey: LEXMMFPAPDGYGZ-UHFFFAOYSA-N
Solubility: DMSO 86 mg/mL (207
Smiles: CC1C(=CC=CC=1COC1C=C(OC)C(CN2CCCC[C@H]2C(O)=O)=C(C=1)OC)C1=CC=CC=C1
Repeat administration of AS2034178 enhanced insulin sensitivity in an insulin tolerance test and a euglycemic-hyperinsulinemic clamp test
Vicriviroc maleate - CAS# 599179-03-0 Size:Solid 2 mg Abstract #250Vicriviroc, also known as SCH 417690, MK 7690 and SCH D, is a potent, orally active and selective CCR5 entry inhibitor of HIV 1 (IC50 = 0. 91 nM). Vicriviroc effectively inhibits the initial stages of the virus life cycle. Vicriviroc demonstrated synergistic anti HIV activity in combination with drugs from all other classes of approved antiretrovirals. Vicriviroc binds with higher affinity to CCR5 than SCH C. Functional assays, including inhibition of
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