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and shows low affinities at D1 and D4 receptors (Ki = 3 and 0
Smiles: CC1C2=NC(=NC(=C2SC=1CN1CCN(CC1)C(=O)[C@H](C)O)N1CCOCC1)C1=CN=C(N)N=C1
11-pentaen-11-yl]pyridin-2-yl}methyl)acetamide
2021 Jan 7
Chemical Name: 4-amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2
MPT0E028 Catalog No.:M26129-C and shows low affinities atMPT0E028 is an orally active and selective HDAC inhibitor with IC50s of 53. 0 nM, 106. 2 nM, 29. 5 nM for HDAC1, HDAC2 and HDAC6, respectively. MPT0E028 reduces the viability of B cell lymphomas by inducing apoptosis and possesses potent direct Akt targeting ability and reduces Akt phosphorylation in B cell lymphoma. MPT0E028 has good anticancer activity. Product information CAS Number: 1338320 94 7 Molecular Weight: 344. 38 Formula: C17H16N2O4S
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