Thalidomide-O-C10-NH2 AS inhibitor Smiles: CC(C)COC(=O)C1C(C2=CC=CC=C2[N+]([O-])=O)C(C(=O)OC)=C(C)NC=1C

Smiles: CC(C)COC(=O)C1C(C2=CC=CC=C2[N+]([O-])=O)C(C(=O)OC)=C(C)NC=1C

PubMed PMID: 26327464

TAME at concentration of 1-200 μM arrests interphase extract treated with recombinant cyclin B1/Cdc2 complex in mitosis

InChiKey: JCINBYQJBYJGDM-UHFFFAOYSA-N

Mitoxantrone shows cytotoxicity to human breast carcinoma cell lines MDA-MB-231 and MCF-7 with IC50 values of 18 and 196 nM

Thalidomide-O-C10-NH2 AS inhibitor Smiles: CC(C)COC(=O)C1C(C2=CC=CC=C2[N+]([O-])=O)C(C(=O)OC)=C(C)NC=1CThalidomide O C10 NH2 is a synthesized E3 ligase ligand linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. Product information CAS Number: 1957236 08 6 Molecular Weight: 429. 51 Formula: C23H31N3O5 Chemical Name: 4 [(10 aminodecyl)oxy] 2 (2, 6 dioxopiperidin 3 yl) 2, 3 dihydro 1H isoindole 1, 3 dione Smiles: NCCCCCCCCCCOC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O InChiKey: GYCOQQKBPGDRKH