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2009 Aug 20
and the IC50 value of the compound against CaM-KII is 10 μg/mL
GJ-103 sodium
TA 02 and SB203580 reduce the nuclear TCF/LEF-1 driven transcription of luciferase similar to DKK-1
18(17):4764-74
FLI-06 - Notch Pathway Modulator. CAS# 313967-18-9 Catalog No.:M60149-10S 2009 Aug 20FLI 06, CAS No. 313967 18 9, is a novel potent and selective small molecule intercepting Notch signaling and the early secretory pathway (EC50 ~2. 3 M), identified by using automated microscopy to monitor the trafficking and processing of a ligand independent Notch GFP fusion reporter. FLI 06 can induce accumulation of the reporter at the plasma membrane by interfering with transport in the secretory pathway. It can also disrupt the Golgi apparatus in