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Silodosin-d4 ac)-PF-06250112 Chemical Name: 4-(4-chloro-3-hydroxy-5

SKU: 15470150926

4.2
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Description

Chemical Name: 4-(4-chloro-3-hydroxy-5

151:104567

Chemical Name: 1-[3-(4-{2-[(4-chloro-5-cyclopropyl-2-hydroxyphenyl)amino]acetyl}piperazin-1-yl)azetidin-1-yl]prop-2-en-1-one

IMP-1088 has a Kd of <210 pM for HsNMT1

while higher doses lead to intestinal toxicity

Silodosin-d4 ac)-PF-06250112 Chemical Name: 4-(4-chloro-3-hydroxy-5Silodosin d4 (KAD 3213 d4) is the deuterium labeled Silodosin. Silodosin (KAD 3213) is a potent, selective and orally active 1A adrenergic receptor (1A AR) blocker. Silodosin exhibits high affinity for 1A AR (Ki=0. 036 nM), over 162 fold and 50 fold than for 1B AR and 1D AR with Ki values of 21 nM and 2. 0 nM, respectively. Silodosin is an effective and well tolerated agent, it can be used for the investigation of LUTS BPH. Product information CAS

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