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The MDL29951-activated receptor exhibits other activities associated with GPCR-mediated signaling
CAS Number: 1621175-65-2
InChi: InChI=1S/C23H24N6/c1-16(2)20-6-4-5-7-21(20)23-24-14-17(3)22(27-23)25-15-18-8-10-19(11-9-18)29-13-12-26-28-29/h4-14
Chemical Name: N-((6-(hydroxyamino)-6-oxohexyl)oxy)-3
and ~1 µM for JMJD3 (KDM6B) and JMJD2C (KDM4C)
BIX-02188 - CAS# 334949-59-6 Catalog No.:M60430-2S The MDL29951-activated receptor exhibits otherBIX 02188, CAS No. 334949 59 6, is a potent inhibitor of MEK5 (IC50 = 4. 3 nM) with reduced activity towards inhibition of ERK5 and TGFR1 (IC50s = 810 and 1, 800 nM, respectively). Inhibition of MEK5 by BIX 02188 induces apoptosis in cells expressing the oncogenic mutant FLT3 ITD. Product information CAS Number: 334949 59 6 Molecular Weight: 412. 48 Formula: C25H24N4O2 Chemical Name: (Z) 3 (((3 ((dimethylamino)methyl)phenyl)amino)(phenyl)methylene) 2
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