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HE-3235 5217 8-dihydroxy-6-methoxy-2H-chromen-2-one

SKU: 16051971126

4.7
USD100.00 USD126.00

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Description

8-dihydroxy-6-methoxy-2H-chromen-2-one

InChi: InChI=1S/C19H20N6O6/c20-24-22-9-2-1-8-21-15(27)10-31-13-5-3-4-11-16(13)19(30)25(18(11)29)12-6-7-14(26)23-17(12)28/h3-5

is a synthetic light-activated chlorin with photodynamic activity

40-octakis(hydroxymethyl)-2

BPTES inhibits the allosteric activation caused by phosphate binding and promotes the formation of an inactive complex

HE-3235 5217 8-dihydroxy-6-methoxy-2H-chromen-2-oneHE 3235 is a novel antagonist of androgen receptor. Androgen receptor (AR) is an adrenal hormone belongs to the steroid hormone receptor family of molecules. AR is responsible for mediating the physiologic effects of androgens by binding to specific DNA sequences that influence transcription of androgen responsive genes. Variations in the AR gene may lead to genetic predisposition to prostate cancer development and severity . In vitro: In LNCaP cells

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