Rapamycin-d3 - CAS# 392711-19-2 0584 2369068-42-6

2369068-42-6

Smiles: CN1C=C2C=C(C=CC2=N1)SC1=NN=C2C=CC(=NN21)C1C=NN(C)C=1

CK-1827452 demonstrates good PK parameters in both rats (Sprague−Dawley) and dogs (Beagle) with clearances of 22 and 7

Jaspamycin (7-CN-7-C-Ino) is a potent activator of PKA

Smiles: CCOC/C=C/C1C=CC(=CC=1)C1NC(=C(N=1)C1C=CC(=CC=1)NC(C)C)C1C=CC(=CC=1)NC(C)C

Rapamycin-d3 - CAS# 392711-19-2 0584 2369068-42-6Rapamycin d3 (Sirolimus d3) is the deuterium labeled Rapamycin. Rapamycin is a potent and specific mTOR inhibitor with an IC50of 0. 1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant. Product information CAS Number: 392711 19 2 Molecular Weight: 917. 19 Formula: C51H79NO13 Synonym: Sirolimus d3 AY 22989 d3 Chemical Name: (1R, 9S, 12S,