BIO5192 hydrate Size:Contact [email protected] for quotation COC1=CC2CC(=O)N(CCCNC[C@H]3CC4=CC(OC)=C(C=C43)OC)CCC=2C=C1OC

COC1=CC2CC(=O)N(CCCNC[C@H]3CC4=CC(OC)=C(C=C43)OC)CCC=2C=C1OC

Enhancement of proteasome activity through inhibition of Usp14 may offer a strategy to reduce the levels of aberrant proteins in cells under proteotoxic stress

and C271Y) in HEK293 cells

InChiKey: QTGFSGVSWOBQLB-WMOHYEITSA-N

PubMed PMID: 25108436

BIO5192 hydrate Size:Contact [email protected] for quotation COC1=CC2CC(=O)N(CCCNC[C@H]3CC4=CC(OC)=C(C=C43)OC)CCC=2C=C1OCBIO5192 hydrate is a selective and potent integrin 41 (VLA 4) inhibitor (Kd<10 pM). BIO5192 hydrate selectively binds to 41 (IC50=1. 8 nM) over a range of other integrins. BIO5192 hydrate results in a 30 fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels. Product information Molecular Weight: 826. 79 Formula: C76H94Cl4N12O17S2 Chemical Name: bis((2S) 2 {[(2S) 1 (3,5 dichlorobenzenesulfonyl)pyrrolidin 2