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It may potentially evade drug resistance in cancer cells
Srivastava M
Napabucasin (BBI608)
TAE684 inhibits the proliferation of Ba/F3 NPM-ALK cells with an ICsub>50 of 3 nM
Daidzein-2c
Nocodazole - Microtubule Inhibitor / CRISPR Editing Enhancer. CAS# 31430-18-9 60239 It may potentially evade drugNocodazole, CAS No. 31430 18 9, is a potent microtubule inhibitor to inhibit mitosis. It disrupts microtubules by binding to tubulin and preventing formation of one of the two interchain disulfide linkages, thus inhibiting microtubule dynamics, disruption of mitotic spindle function, and fragmentation of the Golgi complex. Nocodazole arrests the cell cycle at G2 M phase and also prevents phosphorylation of the T cell antigen receptor and inhibits its
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