BAY 60-6583 Catalog No.:M20093-C Smiles: N#CC1C=C(C=C2C=CC(O)=CC2=1)C1C=C(F)C(O)=CC=1

Smiles: N#CC1C=C(C=C2C=CC(O)=CC2=1)C1C=C(F)C(O)=CC=1

It blocked presentation of LMP7-specific

NF-κβ (p65)

2013 Jun 21

a DNA minor-groove alkylator

BAY 60-6583 Catalog No.:M20093-C Smiles: N#CC1C=C(C=C2C=CC(O)=CC2=1)C1C=C(F)C(O)=CC=1BAY 60 6583 is a potent and high affinity agonist of adenosine A2B receptor (EC50 = 3 nM) over A1, A2A, and A3 receptors. BAY 60 6583 binds to mouse, rabbit, and dog A2BAR with Ki values of 750 nM, 340 nM and 330 nM, respectively. BAY 60 6583 has a cardioprotective effect in a myocardial ischemia model. Product information CAS Number: 910487 58 0 Molecular Weight: 379. 44 Formula: C19H17N5O2S Chemical Name: 2 ({6 amino 3,5 dicyano 4 [4