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ON123300 inhibits CDK6 with an IC50 of 9
5-IP4 (KD=526 μM) for matrix (MA) are almost identical
p-ERK1/2 and cyclin D1/D2 expression in BRAFV600E-mutant A375 cells
at concentrations up to 100 μM
CAS Number: 1000998-59-3
Integrin-IN-2 ylparaben ON123300 inhibits CDK6 with anIntegrin IN 2 (compound 39) is an orally bioavailable pan v integrin inhibitor. Integrin IN 2 can increases the v6, v3, v5 and v8 binding affinities with pIC50 values of 7. 8, 8. 4, 8. 4 and 7. 4, respectively. Product information CAS Number: 2378617 67 3 Molecular Weight: 458. 55 Formula: C27H30N4O3 Chemical Name: 3 (3 cyclopropylphenyl) 3 ({5 [2 (5,6,7,8 tetrahydro 1,8 naphthyridin 2 yl)ethoxy]pyridin 2 yl}amino)propanoic acid Smiles:
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