BRD7-IN-1 Catalog No.:M15257-2 Smiles: CC1=CC=CC=C[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)C(C)=C[C@@H](C)C(=O)C[C@H](OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@H](C[C@@H]1OC)CC[C@H]2C)[C@H](C)C[C@H]1C[C@@H](OC)[C@@H](CC1)OP(C)(C)=O |c:1

Name: BRD7-IN-1 Catalog No.:M15257-2 Smiles: CC1=CC=CC=C[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)C(C)=C[C@@H](C)C(=O)C[C@H](OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@H](C[C@@H]1OC)CC[C@H]2C)[C@H](C)C[C@H]1C[C@@H](OC)[C@@H](CC1)OP(C)(C)=O |c:1
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Description

Smiles: CC1=CC=CC=C[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)C(C)=C[C@@H](C)C(=O)C[C@H](OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@H](C[C@@H]1OC)CC[C@H]2C)[C@H](C)C[C@H]1C[C@@H](OC)[C@@H](CC1)OP(C)(C)=O |c:1

34-15-/t26-

InChiKey: VJKZMXOJMQCHRI-AXPXABNXSA-N

CAS Number: 134381-21-8

CAS Number: 785835-79-2

BRD7-IN-1 Catalog No.:M15257-2 Smiles: CC1=CC=CC=C[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)C(C)=C[C@@H](C)C(=O)C[C@H](OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@H](C[C@@H]1OC)CC[C@H]2C)[C@H](C)C[C@H]1C[C@@H](OC)[C@@H](CC1)OP(C)(C)=O |c:1BRD7 IN 1, a modified derivative of BI7273 (BRD7 9 inhibitor), binds to a VHL ligand via a linker to form a PROTAC VZ185 (VZ185 against BRD7 9 with DC50s of 4. 5 and 1. 8 nM, respectively). Product information CAS Number: 2448414 48 8 Molecular Weight: 467. 39 Formula: C22H28Cl2N4O3 Chemical Name: 4 {3,5 dimethoxy 4 [(piperazin 1 yl)methyl]phenyl} 2 methyl 1,2 dihydro 2,7 naphthyridin 1 one dihydrochloride Smiles: Cl. Cl.

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