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InChiKey: VEWFTYOFWIXCIO-UHFFFAOYSA-N
CAS Number: 193000-39-4
is a potent and specific CYP1B1 inhibitor
TA 02 at 5 μM concentration induces cardiogenesis
Molecular Weight: 357
Etoposide yrphostin A1 InChiKey: VEWFTYOFWIXCIO-UHFFFAOYSA-NEtoposide is a semisynthetic derivative of podophyllotoxin and a substance extracted from the mandrake root Podophyllum peltatum. Possessing potent antineoplastic properties, etoposide binds to and inhibits topoisomerase II and its function in ligating cleaved DNA molecules, resulting in the accumulation of single or double strand DNA breaks, the inhibition of DNA replication and transcription, and apoptotic cell death. Etoposide acts primarily in the
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