BMS-690514 Catalog No.:M10884-10 Reversine is also a novel

Reversine is also a novel Aurora kinases inhibitor that inhibits colony formation of human acute myeloid leukemia cells

Smiles: COC1=CC(=CC=C1)C1C=CC(=CC=1)[C@@H](OC1=CC(=NC(N)=N1)C1C=CC(C[C@H](N)C(O)=O)=CC=1)C(F)(F)F

This is consistent across both models

3-thiazol-2-yl)ethyl]carbamoyl}ethyl]pyrrolidin-1-yl]-5-methyl-1-oxoheptan-4-yl](methyl)carbamoyl}-2-methylpropyl]carbamoyl}-2-methylpropyl]-N-methylcarbamate

LDK 378 dihydrochloride

BMS-690514 Catalog No.:M10884-10 Reversine is also a novelBMS 690514 is a potent inhibitor of human epidermal growth factor receptor (HER) 1 (EGFR), 2, and 4, and vascular endothelial growth factor receptors (VEGFR) 1 3. BMS 690514 is currently under investigation as an oral agent for the treatment of solid tumors. In vitro and in vivo studies were conducted to characterize the pharmacokinetics and metabolism. Through integration of in vitro and in vivo pharmacokinetic data and antitumor efficacy in nude