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JP1302 dihydrochloride 7736 PF 03716556

SKU: 20718736822

4.7
USD100.00 USD147.00

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Description

PF 03716556

This specificity for μ-opioid receptors and limited penetrability into the brain prevent Loperamide from demonstrating central systemic effects generally associated with opiates

Mitoguazone is a brain-penetrant and competitive S-adenosyl-methionine decarboxylase (SAMDC) inhibitor that disrupts polyamine biosynthesis

Smiles: C[C@@H](O[C@H]1OCCN(CC2NC(=O)N(N=2)P(O)(O)=O)[C@H]1C1C=CC(F)=CC=1)C1C=C(C=C(C=1)C(F)(F)F)C(F)(F)F

InChi: InChI=1S/C26H24FN3O6/c1-3-26(35)15-6-19-23-13(8-30(19)24(33)14(15)10-36-25(26)34)22-17(28-20(32)9-31)5-4-12-11(2)16(27)7-18(29-23)21(12)22/h6-7

JP1302 dihydrochloride 7736 PF 03716556JP1302 dihydrochloride is a selective, high affinity antagonist of the alpha2C adrenoceptor (2C adrenoceptor), with a Kb value (antagonist activity) of 16 nM and a Ki (binding affinity) value of 28 nM. Product information CAS Number: 1259314 65 2 Molecular Weight: 441. 40 Formula: C24H26Cl2N4 Chemical Name: N [4 (4 methylpiperazin 1 yl)phenyl] 9,10 dihydroacridin 9 imine dihydrochloride Smiles: Cl. Cl.

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