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A 410099.1 amide-PEG4-amine - CAS# 2446474-10-6 0331 Bioorg Chem

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Description

Bioorg Chem

is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity

Prolonged treatment with pimelic o-aminobenzamide HDAC inhibitors ameliorates the disease phenotype of a Friedreich ataxia mouse model

is a potent and selective WD repeat-containing protein 5 (WDR5) antagonist (Kd ~24-52 nM)

It inhibits phosphorylation of the mTORC1 substrates 4E-BP1 and S6K1 as well as the mTORC2 substrate AKT in diverse cancer models in vitro and in vivo

A 410099.1 amide-PEG4-amine - CAS# 2446474-10-6 0331 Bioorg ChemA 410099. 1 amide PEG4 amine, CAS No. 2446474 10 6, IAP ligand with PEG linker and terminal amine for onward chemistry Functionalized IAP ligand for PROTAC research and development; incorporates an IAP ligand plus an amide PEG4 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. Product information CAS Number: 2446474 10 6 Molecular Weight: 817. 02 Formula:

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