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with an IC50 of 200 nM
(2012) Mol Pharmacol
6-diethoxy-1-benzothiophene-2-carboxylate
InChi: InChI=1S/C13H11FN2O3/c14-8-2-1-7-6-16(13(19)9(7)5-8)10-3-4-11(17)15-12(10)18/h1-2
Smiles: CN(C1CC23CCCCC2=CN2C=CCCC2=C3O1)S(=O)(=O)CCO
GNE 2861 idone D8 with an IC50 of 200GNE 2861 is a PAK inhibitor that displays group II selectivity. GNE 2861 inhibits PAK4, PAK5 and PAK6 with IC50s of 7. 5, 36, 126 nM, respectively. Product information CAS Number: 1394121 05 1 Molecular Weight: 406. 48 Formula: C22H26N6O2 Chemical Name: 1 {2 [1 (2 aminopyrimidin 4 yl) 2 [(2 methoxyethyl)amino] 1H 1,3 benzodiazol 6 yl]ethynyl}cyclohexan 1 ol Smiles: COCCNC1=NC2=CC=C(C=C2N1C1C=CN=C(N)N=1)C#CC1(O)CCCCC1 InChiKey: RZXMIHOUHYSGJO
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