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Smiles: CS(=O)/C=C/CCN=C=S
Chemical Name: (2S)-2-amino-3-[(2-diazoacetyl)oxy]propanoic acid
CDK9 inhibitor is a small-molecule selective inhibitor of CDK9 (cyclin dependent kinase 9) with IC50 value of 39 nM
only one group shows a significant result
t-test) at 6 h in response to the Motolimod (VTX-2337) treatment (10 mg/kg)
CP-465022 (maleate) hrin-β Smiles: CS(=O)/C=C/CCN=C=SIC50: 25 nM for AMPA receptor mediated currents in rat cortical neurons CP 465022 is an AMPA antagonist. The inhibition of alpha amino 3 hydroxy 5 methyl 4 isoxazolepropionic acid (AMPA) receptor has been hypothesized to lead to neuroprotective efficacy after cerebral ischemia on the basis of the activity in ischemia models of a variety of compounds with varying selectivity for AMPA over other glutamate receptor subtypes. In vitro: CP 465022 inhibited
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