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5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-3-(((2S
dose-dependent inhibition of tumor growth (up to 75% TGI) was observed at doses ranging from 3 to 30 mg/kg
InChiKey: FQYZPSNPTJYQKB-UHFFFAOYSA-N
CAS Number: 129101-54-8
Formula: C34H44N4O9
VEGFR-3-IN-1 lorin 5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-3-(((2SVEGFR 3 IN 1 is a potent and selective VEGFR3 inhibitor with an IC50 of 110. 4 nM. VEGFR 3 IN 1 significantly inhibits proliferation and migration of VEGF C induced human dermal lymphatic endothelial cells (HDLEC), MDA MB 231, and MDA MB 436 cells by inactivating the VEGFR3 signaling pathway, and also effectively inhibits breast cancer growth. Product information Molecular Weight: 616. 10 Formula: C29H29ClF3N7OS Chemical Name: N (4 chloro 3