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M77976 binds to the ATP-binding pocket of PDK4 and causes local conformational changes with complete disordering of the ATP lid
which leads to the suppression of IL-6 synthesis
Cathepsin K inhibitors increase distal femoral bone mineral density in rapidly growing rabbits
InChiKey: BAORCAMWLWRZQG-UHFFFAOYSA-N
Formula: C13H20N2O
Ro24-7429 metasone M77976 binds to the ATP-bindingRo24 7429 is a potent and orally active HIV 1 transactivator protein Tat antagonist. Ro24 7429 is also a runt related transcription factor 1 (RUNX1) inhibitor. Ro24 7429 has anti HIV, antifibrotic and anti inflammatory effects. Product information CAS Number: 139339 45 0 Molecular Weight: 272. 73 Formula: C14H13ClN4 Chemical Name: N [7 chloro 5 (1H pyrrol 2 yl) 2,3 dihydro 1H 1,4 benzodiazepin 2 ylidene]methanamine Smiles: