2014 Jan 1
It is stable to liver microsomes
KI-20227 inhibits disease progression in a collagen-induced arthritis mouse model
(2013) Nature
It can inhibit oncogenic RAS signaling and suppress in vitro and in vivo proliferation of human pancreatic ductal adenocarcinoma cells that are dependent on oncogenic KRAS
(-)-JQ-1 - CAS# 1268524-71-5 size:2mg solid 2014 Jan 1( ) JQ 1, CAS No. 1268524 71 5, is the stereoisomer of (+) JQ1. (+) JQ1 potently decreases expression of both BRD4 target genes, whereas ( ) JQ 1 Enantiomer has no effect. Product information CAS Number: 1268524 71 5 Molecular Weight: 456. 99 Formula: C23H25ClN4O2S Chemical Name: 6H Thieno[3, 2 f][1, 2, 4]triazolo[4, 3 a][1, 4]diazepine 6 acetic acid, 4 (4 chlorophenyl) 2, 3, 9 trimethyl , 1, 1 dimethylethyl ester, (6R) Smiles: