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50 uM/20 uM compound concentration's inhibitory percentage are 75%/67% for chitinase/N- acetyl-hexosaminidase respectively
RITA (1 μM) stabilizes p53 by inhibiting p53/E6AP interaction
cardiovascular protective
PI3K/mTOR kinase inhibitor GDC-0980 inhibits both PI3K kinase and mTOR kinase
Chemical Name: 2-[4-(1-{1-[7-fluoro-3-(1-methyl-1H-pyrazol-4-yl)quinolin-6-yl]ethyl}-1H-[1
(Rac)-Calpain Inhibitor XII inib bromide 50 uM/20 uM compound concentration's(Rac) Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I ( calpain, Ki=19 nM). (Rac) Calpain Inhibitor XII has lower affinities for calpain II (m calpain, Ki=120 nM) and cathepsin B (Ki=750 nM). (Rac) Calpain Inhibitor XII has the potential for studying the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury. Product information CAS Number: 181769 57 3