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2012 Apr 1
16(7):e314
InChi: InChI=1S/C16H17Cl2N5O2/c17-10-2-1-3-11(18)13(10)15(24)22-12-8-20-23-14(12)16(25)21-9-4-6-19-7-5-9/h1-3
Baricitinib inhibits IL-6-stimulated phosphorylation of the canonical substrate STAT3 (pSTAT3) and subsequent production of the chemokine MCP-1 with IC50 values of 44 nM and 40 nM
25)5)11-12-22-16-23(28)17-26(29)20(22)4/h11-12
Exherin trifluoroacetate - CAS# 1135237-88-5 hemisulfate 2012 Apr 1Exherin TFA salt, also known as ADH 1 TFA, is the TFA salt form of exherin, which is a small, cyclic pentapeptide vascular targeting agent with potential antineoplastic and antiangiogenic activities. ADH 1 selectively and competitively binds to and blocks N cadherin, which may result in disruption of tumor vasculature, inhibition of tumor cell growth, and the induction of tumor cell and endothelial cell apoptosis. N cadherin, a cell surface
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