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428(2):298-302
5S)-6-hydroxy-6-(H)methyl-5-methyl(7
XL647 binds to and inhibits several tyrosine receptor kinases that play major roles in tumor cell proliferation and tumor vascularization
Chemical Name: 2-(3-fluoro-4-hydroxyphenyl)-7-vinylbenzo[d]oxazol-5-ol
Tedeschi A
VTP-27999 TFA - a renin inhibitor. CAS# 1013937-63-7 Size:Solid 10 mg 428(2):298-302VTP 27999 is a highly potent and selective renin inhibitor (IC50 = 0. 47 nM). VTP 27999 demonstrated excellent selectivity over related and unrelated off targets, >15% oral bioavailability in three species, oral efficacy in a double transgenic rat model of hypertension, and good exposure in humans. Product information CAS Number: 1013937 63 7 Molecular Weight: 639. 10 Formula: C28H42ClF3N4O7 Synonym: VTP 27999, 2, 2, 2 trifluoroacetate VTP27999, 2, 2,
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