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28)29)6-7-20(19)37(18)23(39)41-5-2)36(22(38)40-3)13-14-8-16(25(30
AZD7762 binds to and inhibits Chks
Oral gavage daily for 8 days) treatment shows excellent in vivo efficacy in a rat model of joint inflammation
Smiles: CN(OC)C(=O)N1N=C(S[C@]1(CCCN)C1C=CC=CC=1)C1=CC(F)=CC=C1F
BI-3663 potently degrades PTK2 in Hep3B2
Sacubitril-d4 21718 28)29)6-7-20(19)37(18)23(39)41-5-2)36(22(38)40-3)13-14-8-16(25(30Sacubitril d4 (AHU 377 d4) is the deuterium labeled Sacubitril. Sacubitril (AHU 377) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril (AHU 377) is a component of the heart failure medicine LCZ696. Product information CAS Number: 1884269 07 1 Molecular Weight: 415. 52 Formula: C24H29NO5 Chemical Name: 3 {[(2S,4R) 1 {[1,1' biphenyl] 4 yl} 5 ethoxy 4 methyl 5 oxopentan 2 yl]carbamoyl}(H)propanoic acid Smiles:
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