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PSI ibitor peptide 18 InChi: InChI=1S/C25H25N3O8S2/c1-15-12-26-21(16(2)24(15)35-4)14-37(31)25-27-20-11-18(34-3)7-10-22(20)28(25)38(32

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Description

InChi: InChI=1S/C25H25N3O8S2/c1-15-12-26-21(16(2)24(15)35-4)14-37(31)25-27-20-11-18(34-3)7-10-22(20)28(25)38(32

acts as a chain-elongating inhibitor of DNA polymerase

Clofilium (10 μM

[Epub ahead of print] PubMed PMID: 31776128

(Rac)-BAY1238097 is a BET inhibitor

PSI ibitor peptide 18 InChi: InChI=1S/C25H25N3O8S2/c1-15-12-26-21(16(2)24(15)35-4)14-37(31)25-27-20-11-18(34-3)7-10-22(20)28(25)38(32ZIE(OtBu)AL CHO (PSI)1 have been shown to inhibit the proteasome activities in a variety of cell types. Peptide aldehyde, PSI (Z Ile Glu(OtBu) Ala Leu al), inhibits the proteasome 10 fold better than calpain but is less potent than MG1322. Since MG132, PSI, MG115 (Z Leu Leu nVal al) and ALLN can all inhibit calpains and various lysosomal cathepsins in addition to the proteasome, when using these inhibitors in cell culture it is important to perform

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