CCR2 antagonist 1 asidenib (AG-881) 60)23(12)22-11(37(57)66-33)5-17(46)27(51)31(22)68-41)18(63-39)7-62-35(55)9-3-15(44)25(49)28(52)20(9)21-10(36(56)65-32)4-16(45)26(50)29(21)53/h1-6

60)23(12)22-11(37(57)66-33)5-17(46)27(51)31(22)68-41)18(63-39)7-62-35(55)9-3-15(44)25(49)28(52)20(9)21-10(36(56)65-32)4-16(45)26(50)29(21)53/h1-6

InChiKey: IBPLNKRENHFZJM-AYPAWVCOSA-N

13-acetyl-9-Dihydrobaccatin III is a taxane originally isolated from T

InChiKey: JJEDWBQZCRESJL-DEDYPNTBSA-N

hyperplasia

CCR2 antagonist 1 asidenib (AG-881) 60)23(12)22-11(37(57)66-33)5-17(46)27(51)31(22)68-41)18(63-39)7-62-35(55)9-3-15(44)25(49)28(52)20(9)21-10(36(56)65-32)4-16(45)26(50)29(21)53/h1-6CCR2 antagonist 1 is a high affinity and long residence time CCR2 antagonist, with a Ki of 2. 4 nM. Product information CAS Number: 1683534 96 4 Molecular Weight: 549. 47 Formula: C28H32BrF3N2O Chemical Name: (1R) 5 bromo N [(1R,3S) 3 (propan 2 yl) 3 [7 (trifluoromethyl) 1,2,3,4 tetrahydroisoquinoline 2 carbonyl]cyclopentyl] 2,3 dihydro 1H inden 1 amine Smiles: CC(C)[C@]1(C[C@@H](CC1)N[C@@H]1CCC2C=C(Br)C=CC=21)C(=O)N1CC2C=C(C=CC=2CC1)C(F)(F)F