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TAK-960 - CAS# 1137868-52-0 Catalog No.:M6675-10 higher doses than those required

SKU: 27293978507

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Description

higher doses than those required for anticonvulsant efficacy of the drugs were needed for activity in the reversal-learning model

AR7 is the first small molecule developed to selectively stimulate CMA without affecting macroautophagy

a JMJD2 demethylase inhibitor with demonstrated antiviral activity

is a novel dual PI3K/mTOR inhibitor with an IC50 ~1 nM

CC-930 inhibits the formation of phospho-cJun in human PBMC stimulated by phorbol-12-myristate-13-acetate and phytohemeagglutinin (IC50=1 μM)

TAK-960 - CAS# 1137868-52-0 Catalog No.:M6675-10 higher doses than those requiredTAK 960, CAS No. 1137868 52 0, is a n orally available PLK1 inhibitor with potential antineoplastic activity. Polo like kinase 1 inhibitor TAK 960 selectively inhibits PLK1, inducing selective G2 M cell cycle arrest followed by apoptosis in a variety of tumor cells while causing reversible cell cycle arrest at the G1 and G2 stages without apoptosis in normal cells. PLK1 inhibition may result in the inhibition of proliferation in PLK1 overexpressed

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