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6-trimethyl-4-(tetradecanoyloxy)cyclohex-2-en-1-yl]octadeca-1
The vitamin D prodrugs 1alpha(OH)D2
A xenograft study is performed using NCr/nude mice implanted with MDA-MB 231 and SUM 149 cell lines
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KPT-9274 Size:Contact [email protected] for quotation 6-trimethyl-4-(tetradecanoyloxy)cyclohex-2-en-1-yl]octadeca-1KPT 9274 is a selective and orally bioavailable allosteric inhibitor of PAK4 . P21 protein (Cdc42 Rac) activated kinase 4 (PAK4) is a serine threonine protein kinase and a member of the PAK family of proteins which are Rac1 and Cdc42 effectors. PAK4 is a mediator of filopodia formation and stabilizes catenin transcriptional activity, and is involved in disease progression for several solid tumors . KPT 9274 is a selective and orally bioavailable PAK4
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