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Trimethylamine N-oxide - CAS# 1184-78-7 60140 Manning Fox JE

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Description

Manning Fox JE

Pharmacol Res

Chemical Name: 2-nitro-5-tosylfuran

An unusually steep structure-activity relationship for analogues of 4-(3-bromoanilino)-6

remarkably decreases the isoproterenol-induced formation of clathrin-coated vesicles and the β2AR-GFP fusion protein remained on the plasma membrane in HEK-B2 cell line

Trimethylamine N-oxide - CAS# 1184-78-7 60140 Manning Fox JETrimethylamine N oxide, CAS No. 1184 78 7, is a gut microbe dependent metabolite of dietary choline and other trimethylamine containing nutrients. Trimethylamine N oxide induces inflammation by activating the ROS NLRP3 inflammasome. Trimethylamine N oxide also accelerates fibroblast myofibroblast differentiation and induces cardiac fibrosis by activating the TGF smad2 signaling pathway. Product information CAS Number: 1184 78 7 Molecular Weight: 75.

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