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In several hypertension rat models
is a potent and selective CBP/ EP300 bromodomain inhibitor
26)27)9-12-19(20)22(31)29-23-28-21(14-34-23)16-5-3-2-4-6-16/h2-14
PubMed PMID: 31201552
2016 May 15
SB 203580 Hydrochloride vastatin (Calcium) In several hypertension rat modelsSB 203580 hydrochloride prevents the activation of PKB Akt by inhibiting phosphoinositide dependent protein kinase 1 (PDK1). Product information CAS Number: 869185 85 3 Molecular Weight: 413. 90 Formula: C21H17ClFN3OS Chemical Name: 4 [4 (4 fluorophenyl) 2 (4 methanesulfinylphenyl) 1H imidazol 5 yl]pyridine hydrochloride Smiles: Cl. CS(=O)C1C=CC(=CC=1)C1NC(=C(N=1)C1C=CC(F)=CC=1)C1C=CN=CC=1 InChiKey: WOSGGXINSLMASH UHFFFAOYSA N InChi: InChI=1S
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