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Formula: C27H32N8O2
9 nM (IC50s)for PDE1B in vitro (43
InChi: InChI=1S/C22H17ClN6O/c1-13(28-21-19-20(25-11-24-19)26-12-27-21)17-10-14-6-5-9-16(23)18(14)22(30)29(17)15-7-3-2-4-8-15/h2-13H
PubMed Central PMCID: PMC5207184
Pyridone 6 induces growth inhibition of multiple myeloma cells
CDK8/19i Catalog No.:M7562-2 Formula: C27H32N8O2CDK8 19i is a potent and selective CDK8 and CDK19 inhibitor (IC50 values are 2. 9 and 14. 1 nM, respectively). CDK8 19i maintains pluripotency of mouse PSCs in culture. It induces the formation of dome shaped colonies and upregulates Nanog GFP reporter and endogenous Nanog expression in mouse ESCs in vitro. Product information CAS Number: 923596 52 5 Molecular Weight: 253. 30 Formula: C14H15N5 Chemical Name: N propyl 3 (pyridin 4 yl)imidazo[1,2
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