Pay in 4 interest-free payments of $25.00 Learn more
Ships within 48 hours · Estimated delivery Aug 21 - Aug 26
CDDO-Im also significantly decreases sphere forming efficiency and tumorsphere size in both primary and secondary sphere cultures
InChiKey: BOQQYCYLUTYLGS-UHFFFAOYSA-N
Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties
and enhances Bcl-2 expression
InChiKey: RKDOFSJTBIDAHX-CYHLAULCSA-N
Imatinib hydrochloride in fumarate CDDO-Im also significantly decreases sphereDescription: IC50 Value: 100 nM (PDGFR) ; 100 nM (c Kit) Imatinib is a multi target inhibitor of v Abl, c Kit and PDGFR with IC50 of 0. 6 M, 0. 1 M and 0. 1 M, respectively. Imatinib is used to treat chronic myelogenous leukemia (CML), gastrointestinal stromal tumors (GISTs) and a number of other malignancies. in vitro: In vitro assays for inhibition of a panel of tyrosine and serine threonine protein kinases show that Imatinib inhibits the v Abl