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InChi: InChI=1S/C18H19NO4/c1-22-15-7-10-5-12-16-9(3-4-19-12)6-14(21)18(23-2)17(16)11(10)8-13(15)20/h6-8
CAS Number: 1037-50-9
4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-oxa-1-azabicyclo[4
acting as a selective and orally active COX-2 inhibitor
Smiles: OB(O)C1=CC(COC2C=CC(C=C3SC(=O)N(CC4C=CC(F)=CC=4)C3=O)=CC=2)=CC=C1
7-Chloro-4-(piperazin-1-yl)quinoline 171 InChi: InChI=1S/C18H19NO4/c1-22-15-7-10-5-12-16-9(3-4-19-12)6-14(21)18(23-2)17(16)11(10)8-13(15)20/h6-87 Chloro 4 (piperazin 1 yl)quinolone is an important scaffold in medicinal chemistry. 7 Chloro 4 (piperazin 1 yl)quinolone is a potent sirtuin inhibitor and also inhibits the serotonin uptake (IC50 of 50 M). 7 Chloro 4 (piperazin 1 yl)quinolone exhibits antimalarial activity on D10 and K1 strains of P. falciparum with IC50s of 1. 18 M and 0. 97 M, respectively. Product information CAS Number: 837 52 5 Molecular Weight: 247. 72 Formula: C13H14ClN3