Docetaxel gobuvir ) significantly increases the LYVE-1-positive

) significantly increases the LYVE-1-positive areas in tumor tissues in tumor xenograft models using BxPC3 pancreatic adenocarcinoma cells

Vassilev LT

Metformin ameliorates hyperglycemia without stimulating insulin secretion

demonstrates robust in vivo efficacy in multiple models

Formula: C36H56O8

Docetaxel gobuvir ) significantly increases the LYVE-1-positiveDocetaxel, also known as RP 56976, is a semi synthetic, second generation taxane derived from a compound found in the European yew tree Taxus baccata. Docetaxel displays potent and broad antineoplastic properties; it binds to and stabilizes tubulin, thereby inhibiting microtubule disassembly which results in cell cycle arrest at the G2 M phase and cell death. This agent also inhibits pro angiogenic factors such as vascular endothelial growth factor