Vandetanib Hydrochloride Catalog No.:M9560-10 Smiles: OC1=CC=C2OC3C(=O)NCCCC=3C2=C1

Smiles: OC1=CC=C2OC3C(=O)NCCCC=3C2=C1

0-90 min) induces lysis of Tol+and Tol- strains

Oral administration of Neratinib significantly inhibits the growth of 3T3/neu xenografts

In contrast to VRT-325 and Corr-4a

InChiKey: HEFNNWSXXWATRW-SNVBAGLBSA-N

Vandetanib Hydrochloride Catalog No.:M9560-10 Smiles: OC1=CC=C2OC3C(=O)NCCCC=3C2=C1Vandetanib is an orally bioavailable 4 anilinoquinazoline. Vandetanib selectively inhibits the tyrosine kinase activity of vascular endothelial growth factor receptor 2 (VEGF2), thereby blocking VEGF stimulated endothelial cell proliferation and migration and reducing tumor vessel permeability. This agent also blocks the tyrosine kinase activity of epidermal growth factor receptor (EGFR), a receptor tyrosine kinase that mediates tumor cell